Over the last century the engineering schools teach design for subtractive manufacturing. This design inertia prohibits designers to generate high performance designs when Additive Manufacturing is appropriate. Design practitioners are now enabled to unleash the full potential of AM with the use of Generative Design and Lattice structures within the CAD environment. This presentation will provide an overview of the latest Generative Design and Lattice generation tools. In addition, this presentation will describe a workflow that utilizes the combination Generative Design and Simulation Driven Lattice Structures for High Performance AM Designs. The process will be demonstrated with examples from Aerospace, Defense and Medical industries. The workflow steps are: First the Generative Design spawns optimal feasible design from a set of performance requirements, design rules and manufacturing constraints. The Generative Design uses a set of homogenized material properties generated from the intended lattice unit cell. Second an automatic process generates a CAD model of the Generative Design results. Third using the Generative Design CAD geometry and all the load cases a simulation is performed and the stress results are exported in a three-dimensional field format. Finally, the Generative Design geometry is infilled with a Lattice Structure. The size or density of the lattice structure is driven from the simulation results of the third step. In general, Generative Design solvers optout for speed and not accuracy. A validation step needs to be performed to validate that performance requirements for stress, deflection, buckling, temperature, pressure drop etc. are met. A process that demonstrates the interoperability between the large & complex lattice models and the traditional FEA codes will be presented.